Carvedilol Produces Dose-Related Improvements in Left Ventricular Function and Survival in Subjects With Chronic Heart Failure

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Authors

Michael R. Bristow · University of Colorado Health

Edward M. Gilbert · University of Colorado Health

William T. Abraham · University of Colorado Health

Kirkwood F. Adams · University of Colorado Health

Michael B. Fowler · University of Colorado Health

Ray E. Hershberger · University of Colorado Health

Spencer H. Kubo

Abstract

In subjects with mild to moderate heart failure from systolic dysfunction, carvedilol produced dose-related improvements in LV function and dose-related reductions in mortality and hospitalization rate.

Topics & Keywords

Heart Failure Treatment and Management Cardiovascular and exercise physiology Cardiac pacing and defibrillation studies

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Circulation

Volume 94, Issue 11, pp. 2807-2816

DOI: 10.1161/01.cir.94.11.2807

Field-Weighted Citation Impact: 37.88

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