Corneal Reconstruction with Tissue-Engineered Cell Sheets Composed of Autologous Oral Mucosal Epithelium

20041,515 citationsJournal Articlebronze Open Access

Authors

Kohji Nishida · Osaka University

Masayuki Yamato · Tokyo Women's Medical University

Yasutaka Hayashida · Osaka University

Katsuhiko WATANABE · Osaka University

Kazuaki Yamamoto · Osaka University

Eijiro Adachi · Kitasato University

Shigeru Nagai ·

Abstract

Sutureless transplantation of carrier-free cell sheets composed of autologous oral mucosal epithelial cells may be used to reconstruct corneal surfaces and can restore vision in patients with bilateral severe disorders of the ocular surface.

Topics & Keywords

Corneal Surgery and Treatments Ocular Surface and Contact Lens Corneal surgery and disorders

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 351, Issue 12, pp. 1187-1196

DOI: 10.1056/nejmoa040455

Field-Weighted Citation Impact: 37.53