Sufu and Kif7 in limb patterning and development

201517 citationsJournal Article

Authors

Olena Zhulyn · Hospital for Sick Children

Chi‐Chung Hui · Hospital for Sick Children

Abstract

Together, our findings demonstrate that perturbations of Sufu and Kif7 affect Gli activity and recapitulate the full spectrum of vertebrate limb defects, ranging from severe truncation to polydactyly.

Topics & Keywords

Hedgehog Signaling Pathway Studies Developmental Biology and Gene Regulation Congenital limb and hand anomalies

UN Sustainable Development Goals

Life below water

Publication Details

Published in: Developmental Dynamics

Volume 244, Issue 3, pp. 468-478

DOI: 10.1002/dvdy.24249

Field-Weighted Citation Impact: 1.46