Preoperative Melatonin and Its Effects on Induction and Emergence in Children Undergoing Anesthesia and Surgery

2009106 citationsJournal Articlebronze Open Access

Authors

Zeev N. Kain · Children's Hospital of Orange County

Jill E. MacLaren · Office of the Chief Scientist

Leslie Herrmann · Brown University

Linda C. Mayes · Yale University

Abraham Rosenbaum · University of California, Irvine

Justin Hata · University of California, Irvine

Jerrold Lerman

Abstract

Midazolam is more effective than melatonin in reducing children's anxiety at induction of anesthesia. Melatonin showed a direct dose-dependent effect on emergence delirium.

Topics & Keywords

Pediatric Pain Management Techniques Intensive Care Unit Cognitive Disorders Anesthesia and Sedative Agents

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Anesthesiology

Volume 111, Issue 1, pp. 44-49

DOI: 10.1097/aln.0b013e3181a91870

Field-Weighted Citation Impact: 4.17