Regulatory T-cells and immune tolerance in pregnancy: a new target for infertility treatment?

2009496 citationsReviewbronze Open Access

Authors

Leigh R. Guerin · University of Adelaide

Jelmer R. Prins · University of Groningen

Sarah A. Robertson · University of Adelaide

Abstract

The potency and wide-ranging involvement of Treg cells in immune homeostasis and disease pathology indicates the considerable potential of these cells as therapeutic agents, raising the prospect of their utility in novel treatments for reproductive pathologies.

Topics & Keywords

Reproductive System and Pregnancy Reproductive Physiology in Livestock Immune Cell Function and Interaction

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Human Reproduction Update

Volume 15, Issue 5, pp. 517-535

DOI: 10.1093/humupd/dmp004

Field-Weighted Citation Impact: 10.92