Preoperative versus Postoperative Chemoradiotherapy for Rectal Cancer

20046,016 citationsJournal Article

Authors

Rolf Sauer · Friedrich-Alexander-Universität Erlangen-Nürnberg

Heinz Becker · University of Göttingen

Werner Hohenberger · Friedrich-Alexander-Universität Erlangen-Nürnberg

Claus Rödel · Friedrich-Alexander-Universität Erlangen-Nürnberg

Christian Wittekind · Leipzig University

Rainer Fietkau · University of Rostock

Peter Martus

Abstract

Preoperative chemoradiotherapy, as compared with postoperative chemoradiotherapy, improved local control and was associated with reduced toxicity but did not improve overall survival.

Topics & Keywords

Colorectal Cancer Surgical Treatments Colorectal and Anal Carcinomas Gastric Cancer Management and Outcomes

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 351, Issue 17, pp. 1731-1740

DOI: 10.1056/nejmoa040694

Field-Weighted Citation Impact: 82.10