Finishing a whole-genome shotgun: Release 3 of the Drosophila melanogastereuchromatic genome sequence

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Authors

S Celniker · Lawrence Berkeley National Laboratory

David A. Wheeler · Baylor College of Medicine

Brent A. Kronmiller · Lawrence Berkeley National Laboratory

Joseph W. Carlson · Lawrence Berkeley National Laboratory

Aaron L. Halpern

Sandeep Patel · Lawrence Berkeley National Laboratory

Mark D. Adams

Mark Champe

Abstract

The WGS strategy can efficiently produce a high-quality sequence of a metazoan genome while generating the reagents required for sequence finishing. However, the initial method of repeat assembly was flawed. The sequence we report here, Release 3, is a reliable resource for molecular genetic experimentation and computational analysis.

Topics & Keywords

Genomics and Phylogenetic Studies RNA and protein synthesis mechanisms Chromosomal and Genetic Variations

UN Sustainable Development Goals

Responsible consumption and production

Publication Details

Published in: Genome biology

Volume 3, Issue 12, pp. RESEARCH0079-RESEARCH0079

DOI: 10.1186/gb-2002-3-12-research0079

Field-Weighted Citation Impact: 14.48