Acute cholestatic liver injury caused by polyhexamethyleneguanidine hydrochloride admixed to ethyl alcohol

201146 citationsJournal Article

Authors

Y. N. Ostapenko · Federal Medical-Biological Agency

Konstantin M. Brusin · Ural State Medical University

Y. V. Zobnin · Irkutsk State Medical University

A. Y. Shchupak · Far Eastern State Medical University

M. K. Vishnevetskiy · Perm State University

В. Г. Сенцов · Ural State Medical University

О. В. Новикова

Abstract

Acute liver injury caused by PHMG-hydrochloride or PHMG in combination with either ethanol or diethyl phthalate can be characterized as cholestatic hepatitis with a severe inflammatory component causing high mortality.

Topics & Keywords

Antimicrobial agents and applications Pneumocystis jirovecii pneumonia detection and treatment Biopolymer Synthesis and Applications

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Clinical Toxicology

Volume 49, Issue 6, pp. 471-477

DOI: 10.3109/15563650.2011.592837

Field-Weighted Citation Impact: 1.54