Cerebrospinal fluid levels of the synaptic protein neurogranin correlates with cognitive decline in prodromal Alzheimer's disease

2014360 citationsJournal Articlegreen Open Access

Authors

Hlin Kvartsberg · University of Gothenburg

Flora H. Duits · Amsterdam Neuroscience

Martin Ingelsson · Uppsala University

Niels Andreasen · Karolinska Institutet

Annika Öhrfelt · University of Gothenburg

Kerstin Andersson · University of Gothenburg

Gunnar Brinkmalm ·

Abstract

These results suggest that CSF Ng is a novel AD biomarker that may be used to monitor synaptic degeneration, and correlates with the rate of cognitive decline in prodromal AD.

Topics & Keywords

Alzheimer's disease research and treatments Neuroscience and Neuropharmacology Research Dementia and Cognitive Impairment Research

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Alzheimer s & Dementia

Volume 11, Issue 10, pp. 1180-1190

DOI: 10.1016/j.jalz.2014.10.009

Field-Weighted Citation Impact: 13.87