Relationship of Circulating Tumor Cells to Tumor Response, Progression-Free Survival, and Overall Survival in Patients With Metastatic Colorectal Cancer

20081,835 citationsJournal Articlegreen Open Access

Authors

Steven J. Cohen · Fox Chase Cancer Center

Cornelis J.A. Punt · Hematology Oncology Associates

Nicholas Iannotti · Duke Medical Center

Bruce Saidman · Duke Medical Center

Kert D. Sabbath · Radboud University Nijmegen

Nashat Gabrail · Hematology Oncology Associates

Joel Picus ·

Abstract

The number of CTCs before and during treatment is an independent predictor of PFS and OS in patients with metastatic colorectal cancer. CTCs provide prognostic information in addition to that of imaging studies.

Topics & Keywords

Cancer Cells and Metastasis Cancer Genomics and Diagnostics Pancreatic and Hepatic Oncology Research

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Journal of Clinical Oncology

Volume 26, Issue 19, pp. 3213-3221

DOI: 10.1200/jco.2007.15.8923

Field-Weighted Citation Impact: 25.20