Altered Hippocampal-Parahippocampal Function During Stimulus Encoding

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Authors

Roberta Rasetti · National Institute of Mental Health

Venkata S. Mattay · National Institutes of Health

Michael G. White · Lieber Institute for Brain Development

Fabio Sambataro · National Institutes of Health

Jamie Podell · National Institute of Mental Health

Brad Zoltick · National Institute of Mental Health

Qiang Chen

Abstract

These results suggest that altered hippocampal-parahippocampal function during encoding is an intermediate biologic phenotype related to increased genetic risk for schizophrenia. Therefore, measuring hippocampal-parahippocampal function with neuroimaging represents a potentially useful approach to understanding genetic mechanisms that confer risk for schizophrenia.

Topics & Keywords

Functional Brain Connectivity Studies Memory and Neural Mechanisms Schizophrenia research and treatment

UN Sustainable Development Goals

Quality Education

Publication Details

Published in: JAMA Psychiatry

Volume 71, Issue 3, pp. 236-236

DOI: 10.1001/jamapsychiatry.2013.3911

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