Goal-directed coagulation management of major trauma patients using thromboelastometry (ROTEM®)-guided administration of fibrinogen concentrate and prothrombin complex concentrate

2010629 citationsJournal Articlegold Open Access

Authors

Herbert Schöchl · Unfallkrankenhaus Salzburg

Ulrike Nienaber · Witten/Herdecke University

Georg Hofer

Wolfgang Voelckel

Csilla Jámbor · München Klinik

Gisela Scharbert · Medical University of Vienna

Sibylle A. Kozek‐Langenecker · Medical University of Vienna

Cristina Solomon

Abstract

ROTEM-guided haemostatic therapy, with fibrinogen concentrate as first-line haemostatic therapy and additional PCC, was goal-directed and fast. A favourable survival rate was observed. Prospective, randomized trials to investigate this therapeutic alternative further appear warranted.

Topics & Keywords

Trauma, Hemostasis, Coagulopathy, Resuscitation Trauma and Emergency Care Studies Hemostasis and retained surgical items

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Critical Care

Volume 14, Issue 2, pp. R55-R55

DOI: 10.1186/cc8948

Field-Weighted Citation Impact: 34.50