Genetic Susceptibility to Cancer

2008469 citationsReviewgreen Open Access

Authors

Linda M. Dong · Fred Hutch Cancer Center

John D. Potter · Fred Hutch Cancer Center

Emily White · Fred Hutch Cancer Center

Cornelia M. Ulrich · Translational Research in Oncology

Lon R. Cardon · Fred Hutch Cancer Center

Ulrike Peters · University of Washington

Abstract

In this review of candidate gene association studies, nearly one-third of gene-variant cancer associations were statistically significant, with variants in genes encoding for metabolizing enzymes among the most consistent and highly significant associations.

Topics & Keywords

Genetic Associations and Epidemiology BRCA gene mutations in cancer Glutathione Transferases and Polymorphisms

Publication Details

Published in: JAMA

Volume 299, Issue 20, pp. 2423-2423

DOI: 10.1001/jama.299.20.2423

Field-Weighted Citation Impact: 26.86

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Genetic Susceptibility to Cancer

Authors

Abstract

Topics & Keywords

Publication Details