Reaction of 2‐(2,2,2‐Trifluoroethylidene)‐1,3‐dithiane 1‐Oxide with Ketones under Pummerer Conditions and Its Application to the Synthesis of 3‐Trifluoromethyl‐Substituted Five‐Membered Heteroarenes

Easy as pie: With the aid of triflic anhydride, the title reaction resulted in nucleophilic attack of the carbonyl oxygen atom onto the activated cationic sulfur center and subsequent [3,3]-sigmatropic rearrangement (see scheme). The products are precursors of the difficult-to-synthesize five-membered 3-trifluoromethyl heteroarene compounds. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.