Dietary Linoleic Acid and Risk of Coronary Heart Disease: A Systematic Review and Meta-Analysis of Prospective Cohort Studies

2014555 citationsReviewgreen Open Access

Authors

Maryam S. Farvid · Brigham and Women's Hospital

Ming Ding · National University Health System

An Pan · National Nutrition and Food Technology Research Institute

Qi Sun · Brigham and Women's Hospital

Stephanie E. Chiuve · Brigham and Women's Hospital

Lyn M. Steffen · Brigham and Women's Hospital

Walter C. Willett

Abstract

In prospective observational studies, dietary LA intake is inversely associated with CHD risk in a dose-response manner. These data provide support for current recommendations to replace saturated fat with polyunsaturated fat for primary prevention of CHD.

Topics & Keywords

Fatty Acid Research and Health Eicosanoids and Hypertension Pharmacology Diet, Metabolism, and Disease

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Circulation

Volume 130, Issue 18, pp. 1568-1578

DOI: 10.1161/circulationaha.114.010236

Field-Weighted Citation Impact: 34.54