Association Between Glutathione S-Transferase P1, T1, and M1 Genetic Polymorphism and Survival of Patients With Metastatic Colorectal Cancer

2002388 citationsJournal Article

Authors

Jan Stoehlmacher · University of Southern California

Abstract

The GSTP1 Ile(105)Val polymorphism is associated in a dose-dependent fashion with increased survival of patients with advanced colorectal cancer receiving 5-FU/oxaliplatin chemotherapy.

Topics & Keywords

Glutathione Transferases and Polymorphisms Genomics, phytochemicals, and oxidative stress BRCA gene mutations in cancer

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: JNCI Journal of the National Cancer Institute

Volume 94, Issue 12, pp. 936-942

DOI: 10.1093/jnci/94.12.936

Field-Weighted Citation Impact: 7.90