Lebrikizumab Treatment in Adults with Asthma

20111,498 citationsJournal Article

Authors

Jonathan Corren · California Allergy and Asthma Medical Group

Robert F. Lemanske

Nicola A. Hanania · Baylor College of Medicine

Phillip E. Korenblat

Merdad V. Parsey · Pacific Biosciences (United States)

Abstract

Lebrikizumab treatment was associated with improved lung function. Patients with high pretreatment levels of serum periostin had greater improvement in lung function with lebrikizumab than did patients with low periostin levels. (Funded by Genentech; ClinicalTrials.gov number, NCT00930163 .).

Topics & Keywords

Asthma and respiratory diseases IL-33, ST2, and ILC Pathways Eosinophilic Esophagitis

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 365, Issue 12, pp. 1088-1098

DOI: 10.1056/nejmoa1106469

Field-Weighted Citation Impact: 85.02