A nanoliposome delivery system to synergistically trigger TLR4 AND TLR7

201479 citationsJournal Articlegold Open Access

Authors

Christopher B. Fox · Infectious Disease Research Institute

Sandra J. Sivananthan · Infectious Disease Research Institute

Malcolm S. Duthie · Infectious Disease Research Institute

Julie Vergara · Infectious Disease Research Institute

Jeffrey A. Guderian · Infectious Disease Research Institute

Elliot Moon

David Coblentz

Steven G. Reed

Abstract

We now have a manufacturable, synergistic TLR4/TLR7 adjuvant that is made with excipients and agonists that are pharmaceutically acceptable and will have a straightforward path into human clinical trials.

Topics & Keywords

Immune Response and Inflammation Immunotherapy and Immune Responses RNA Interference and Gene Delivery

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Journal of Nanobiotechnology

Volume 12, Issue 1, pp. 17-17

DOI: 10.1186/1477-3155-12-17

Field-Weighted Citation Impact: 3.46