Systems Genetics Analysis of Genome-Wide Association Study Reveals Novel Associations Between Key Biological Processes and Coronary Artery Disease

201588 citationsReviewgreen Open Access

Authors

Sujoy Ghosh · National University of Singapore

Juan C. Vivar · Ciência Viva

Christopher P. Nelson · University of Ottawa

Christina Willenborg · Christ University

Ayellet V. Segrè · University of Ottawa

Ville‐Petteri Mäkinen · University of Ottawa

Majid Nikpay ·

Abstract

These findings provide novel insights into how genetic variation, interpreted in the context of biological processes and functional interactions among genes, may help define the genetic architecture of CAD.

Topics & Keywords

Atherosclerosis and Cardiovascular Diseases Genetic Associations and Epidemiology Bioinformatics and Genomic Networks

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Arteriosclerosis Thrombosis and Vascular Biology

Volume 35, Issue 7, pp. 1712-1722

DOI: 10.1161/atvbaha.115.305513

Field-Weighted Citation Impact: 5.40