Familial Evaluation in Catecholaminergic Polymorphic Ventricular Tachycardia

2012168 citationsJournal Article

Authors

Christian van der Werf · Radboud University Nijmegen

Ineke Nederend · University Medical Center Groningen

Nynke Hofman · University of Groningen

Nan van Geloven · University of Groningen

Corné Ebink · Rijnstate Hospital

Ingrid M.E. Frohn-Mulder · Maasstad Ziekenhuis

A. Marco Alings

Abstract

Relatives carrying an Ryr2 mutation show a marked phenotypic diversity. The vast majority do not have signs of supraventricular disease manifestations. Mutation location may be associated with severity of the phenotype. The arrhythmic event rate during follow-up was low.

Topics & Keywords

Cardiac electrophysiology and arrhythmias Ion channel regulation and function Cardiac Arrhythmias and Treatments

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Circulation Arrhythmia and Electrophysiology

Volume 5, Issue 4, pp. 748-756

DOI: 10.1161/circep.112.970517

Field-Weighted Citation Impact: 6.84