Mild Cognitive Impairment and Alzheimer Disease: Regional Diffusivity of Water

2001303 citationsJournal Articlegreen Open Access

Authors

Kejal Kantarci · Mayo Clinic

Clifford R. Jack

Yue Xu · Mayo Clinic

Norberg G. Campeau

Peter C. O’Brien · Mayo Clinic

Glenn E. Smith

Robert J. Ivnik

Bradley F. Boeve

Emre Kokmen · Mayo Clinic

Abstract

Hippocampal ADC was significantly different between control subjects and MCI patients, many of whom likely have preclinical Alzheimer disease. Elevation in hippocampal ADC may reflect early ultrastructural changes in the progression of Alzheimer disease.

Topics & Keywords

Advanced Neuroimaging Techniques and Applications Functional Brain Connectivity Studies Dementia and Cognitive Impairment Research

UN Sustainable Development Goals

Clean water and sanitation

Publication Details

Published in: Radiology

Volume 219, Issue 1, pp. 101-107

DOI: 10.1148/radiology.219.1.r01ap14101

Field-Weighted Citation Impact: 11.48