Long non-coding RNA <i>HNF1A-AS1</i> regulates proliferation and migration in oesophageal adenocarcinoma cells

2013210 citationsJournal Article

Authors

Xue Yang · Johns Hopkins Medicine

Jueping Song · Johns Hopkins Medicine

Yulan Cheng · Johns Hopkins University

Wenjing Wu · Johns Hopkins Medicine

Tushar D. Bhagat · Albert Einstein College of Medicine

Yiting Yu · Albert Einstein College of Medicine

John Abraham ·

Abstract

We have discovered abnormal upregulation of a lncRNA, HNF1A-AS1, in human EAC. Our findings suggest that dysregulation of HNF1A-AS1 participates in oesophageal tumorigenesis, and that this participation may be mediated, at least in part, by modulation of chromatin and nucleosome assembly as well as by H19 induction.

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Published in: Gut

Volume 63, Issue 6, pp. 881-890

DOI: 10.1136/gutjnl-2013-305266

Field-Weighted Citation Impact: 6.52

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Long non-coding RNA <i>HNF1A-AS1</i> regulates proliferation and migration in oesophageal adenocarcinoma cells

Authors

Abstract

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Publication Details