The regulation of toll-like receptor 2 by miR-143 suppresses the invasion and migration of a subset of human colorectal carcinoma cells

201398 citationsJournal Articlegold Open Access

Authors

Haiyan Guo · Shanghai Jiao Tong University

Ying Chen · Shanghai Jiao Tong University

Xiaobo Hu · Shanghai Jiao Tong University

Guanxiang Qian · Shanghai Jiao Tong University

Shengfang Ge · Shanghai Jiao Tong University

Jianjun Zhang · Shanghai Jiao Tong University

Abstract

miR-143 blocks the TLR2 signalling pathway in human CRC cells. This knowledge may pave the way for new clinical applications utilising miR-143 mimics in the treatment of patients with CRC.

Topics & Keywords

MicroRNA in disease regulation Immune Response and Inflammation Cancer-related molecular mechanisms research

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Molecular Cancer

Volume 12, Issue 1, pp. 77-77

DOI: 10.1186/1476-4598-12-77

Field-Weighted Citation Impact: 5.59