The RNA-binding protein hnRNPLL induces a T cell alternative splicing program delineated by differential intron retention in polyadenylated RNA

2014339 citationsJournal Articlegold Open Access

Authors

Vicky Cho · Australian National University

Yan Mei · Australian National University

Arleen Sanny · Bioprocessing Technology Institute

S.M.T. Chan · Australian National University

Anselm Enders · Australian National University

Edward M. Bertram · Australian National University

Andy Hee‐Meng Tan

Abstract

Our findings demonstrate that intron retention in mRNA is induced by specific RNA-binding proteins and suggest a biological significance for this process in marking exons that are poised for alternative splicing.

Topics & Keywords

RNA Research and Splicing RNA modifications and cancer RNA and protein synthesis mechanisms

Publication Details

Published in: Genome biology

Volume 15, Issue 1, pp. R26-R26

DOI: 10.1186/gb-2014-15-1-r26

Field-Weighted Citation Impact: 10.39

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The RNA-binding protein hnRNPLL induces a T cell alternative splicing program delineated by differential intron retention in polyadenylated RNA

Authors

Abstract

Topics & Keywords

Publication Details