Cancer risks in <i>BRCA2</i> families: estimates for sites other than breast and ovary

2005418 citationsletterbronze Open Access

Authors

Christi J. van Asperen · Leiden University Medical Center

R M Brohet · The Netherlands Cancer Institute

E J Meijers-Heijboer · Erasmus MC

N Hoogerbrugge · Radboud University Nijmegen

S Verhoef · Cancer Clinic

H F A Vasen · Netherlands Consortium for Healthy Ageing

M G E M Ausems · University Medical Center Utrecht

F H Menko

Abstract

We found that BRCA2 carriers are at increased risk for cancers of the prostate and pancreas, and possibly bone and pharynx. Larger databases with extended follow up are needed to provide insight into mutation specific risks of selected carriers in BRCA2 families.

Topics & Keywords

BRCA gene mutations in cancer Nutrition, Genetics, and Disease Ovarian cancer diagnosis and treatment

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Journal of Medical Genetics

Volume 42, Issue 9, pp. 711-719

DOI: 10.1136/jmg.2004.028829

Field-Weighted Citation Impact: 9.27