Effect of Peroxisome Proliferator–Activated Receptor-α and -γ Activators on Vascular Remodeling in Endothelin-Dependent Hypertension

2003183 citationsJournal Article

Authors

Marc Iglarz · Montreal Clinical Research Institute

Rhian M. Touyz · Montreal Clinical Research Institute

Farhad Amiri · Montreal Clinical Research Institute

Marie-France Lavoie · Montreal Clinical Research Institute

Quy N. Diep · Montreal Clinical Research Institute

Ernesto L. Schiffrin · Montreal Clinical Research Institute

Abstract

PPAR-alpha and -gamma activators were able to modulate endogenous production of ET-1 and had beneficial vascular effects in endothelin-dependent hypertension.

Topics & Keywords

Peroxisome Proliferator-Activated Receptors Adipose Tissue and Metabolism Nitric Oxide and Endothelin Effects

Publication Details

Published in: Arteriosclerosis Thrombosis and Vascular Biology

Volume 23, Issue 1, pp. 45-51

DOI: 10.1161/01.atv.0000047447.67827.cd

Field-Weighted Citation Impact: 7.21

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Effect of Peroxisome Proliferator–Activated Receptor-α and -γ Activators on Vascular Remodeling in Endothelin-Dependent Hypertension

Authors

Abstract

Topics & Keywords

Publication Details