Use of Fc-Engineered Antibodies as Clearing Agents to Increase Contrast During PET

201430 citationsJournal Articlebronze Open Access

Authors

Rafal Swiercz · The University of Texas Southwestern Medical Center

Srinivas Chiguru · The University of Texas Southwestern Medical Center

Amir Tahmasbi · The University of Texas at Dallas

Saleh Ramezani · The University of Texas Southwestern Medical Center

Guiyang Hao · The University of Texas Southwestern Medical Center

Dilip K. Challa · The University of Texas Southwestern Medical Center

Abstract

Abdegs have considerable potential as agents to stringently regulate antibody dynamics in vivo, resulting in increased contrast during molecular imaging with PET.

Topics & Keywords

Monoclonal and Polyclonal Antibodies Research HER2/EGFR in Cancer Research Radiopharmaceutical Chemistry and Applications

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Journal of Nuclear Medicine

Volume 55, Issue 7, pp. 1204-1207

DOI: 10.2967/jnumed.113.136481

Field-Weighted Citation Impact: 2.96