MicroRNA Expression in Squamous Cell Carcinoma and Adenocarcinoma of the Esophagus: Associations with Survival

2009378 citationsJournal Articlebronze Open Access

Authors

Ewy A. Mathé · Howard Hughes Medical Institute

Giang Huong Nguyen · Virginia Commonwealth University

Elise D. Bowman · Virginia Commonwealth University

Yiqiang Zhao · Virginia Commonwealth University

Anuradha Budhu · Peking University

Aaron J. Schetter · Peking University

Rosemary Braun

Abstract

Our multicenter-based results highlight miRNAs involved in major histologic types of esophageal carcinoma and uncover significant associations with prognosis. Elucidating miRNAs relevant to esophageal carcinogenesis is potentially clinically useful for developing prognostic biomarkers and identifying novel drug targets and therapies.

Topics & Keywords

MicroRNA in disease regulation Circular RNAs in diseases Cancer-related molecular mechanisms research

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Clinical Cancer Research

Volume 15, Issue 19, pp. 6192-6200

DOI: 10.1158/1078-0432.ccr-09-1467

Field-Weighted Citation Impact: 14.29