Overdetection of Recurrence after Radical Prostatectomy: Estimates Based on Patient and Tumor Characteristics

201419 citationsJournal Articlebronze Open Access

Authors

Jing Xia · Fred Hutch Cancer Center

Bruce J. Trock · Johns Hopkins University

Roman Gulati · Fred Hutch Cancer Center

Leslie Mallinger · Fred Hutch Cancer Center

Matthew R. Cooperberg · UCSF Helen Diller Family Comprehensive Cancer Center

Peter R. Carroll · UCSF Helen Diller Family Comprehensive Cancer Center

H. Ballentine Carter

Abstract

This analysis indicates that PSA-R after RP may be overdetected, with risk depending on patient age and tumor characteristics. The potential for overdetection of recurrence confirms the need for approaches to determine whether and when to initiate salvage therapies.

Topics & Keywords

Prostate Cancer Diagnosis and Treatment Prostate Cancer Treatment and Research Health Systems, Economic Evaluations, Quality of Life

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Clinical Cancer Research

Volume 20, Issue 20, pp. 5302-5310

DOI: 10.1158/1078-0432.ccr-13-3366

Field-Weighted Citation Impact: 2.89