Optimal Depth and Duration of Mild Hypothermia in a Focal Model of Transient Cerebral Ischemia

1998322 citationsJournal Articlebronze Open Access

Authors

Carolina M. Maier · Stanford Medicine

Kristine vB. Ahern · Stanford Medicine

Ming Cheng · Stanford Medicine

Jong Eun Lee · Stanford Medicine

Midori A. Yenari · Stanford Medicine

Gary K. Steinberg · Stanford Medicine

Abstract

Intraischemic mild hypothermia must be maintained for 1 to 2 hours to obtain optimal neuroprotection against ischemic cell death due to necrosis and apoptosis.

Topics & Keywords

Thermal Regulation in Medicine Cardiac Arrest and Resuscitation Traumatic Brain Injury and Neurovascular Disturbances

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Stroke

Volume 29, Issue 10, pp. 2171-2180

DOI: 10.1161/01.str.29.10.2171

Field-Weighted Citation Impact: 9.14