The neuroinflammatory response in humans after traumatic brain injury

2012218 citationsJournal Articlegreen Open Access

Authors

Colin Smith · Southern General Hospital

Stephen M. Gentleman · Charing Cross Hospital

Pascale D. Leclercq · Charing Cross Hospital

Lilian S. Murray · Southern General Hospital

W. Sue T. Griffin · Central Arkansas Veterans Healthcare System

David I. Graham · Southern General Hospital

James A. R. Nicoll

Abstract

These results demonstrate that prolonged microglial activation is a feature of traumatic brain injury, but that the neuroinflammatory response returns to control levels after several years.

Topics & Keywords

Neuroinflammation and Neurodegeneration Mechanisms Traumatic Brain Injury and Neurovascular Disturbances S100 Proteins and Annexins

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Neuropathology and Applied Neurobiology

Volume 39, Issue 6, pp. 654-666

DOI: 10.1111/nan.12008

Field-Weighted Citation Impact: 7.82