Adjuvant Chemotherapy in Completely Resected Gastric Cancer: A Randomized Phase III Trial Conducted by GOIRC

2008131 citationsJournal Articlebronze Open Access

Authors

Francesco Di Costanzo · Associazione Italiana Di Oncologia Medica

Silvia Gasperoni · Policlinico Umberto I

L. Manzione · Medica (Italy)

Giancarlo Bisagni · Medica (Italy)

Roberto Labianca · Medica (Italy)

Stefano Bravi · University of Florence

Enrico Cortesi ·

Abstract

Our results failed to provide proof of an effect of adjuvant chemotherapy with PELF on overall survival or disease-free survival. The estimated effect of chemotherapy (10% reduction in the hazard of death or relapse) is modest and consistent with the results of meta-analyses of adjuvant chemotherapy without platinum agents.

Topics & Keywords

Gastric Cancer Management and Outcomes Metastasis and carcinoma case studies Gastrointestinal Tumor Research and Treatment

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: JNCI Journal of the National Cancer Institute

Volume 100, Issue 6, pp. 388-398

DOI: 10.1093/jnci/djn054

Field-Weighted Citation Impact: 9.76