Human Herpesvirus 6 (HHV-6) Reactivation and HHV-6 Encephalitis After Allogeneic Hematopoietic Cell Transplantation: A Multicenter, Prospective Study

2013193 citationsJournal Articlebronze Open Access

Authors

Masao Ogata · Oita University

Takako Satou · Oita University

Jun‐ichi Kadota · Oita University

Noriyuki Saito · Hamanomachi Hospital

Takashi Yoshida · Toyama Prefectural Central Hospital

Hirokazu Okumura · Toyama Prefectural Central Hospital

Toshimitsu Ueki ·

Abstract

High levels of plasma HHV-6 DNA are associated with higher risk of HHV-6 encephalitis. UCBT is a significant risk factor for HHV-6 encephalitis. HHV-6 encephalitis should be considered if CNS dysfunction develops concomitant to high-level plasma HHV-6 DNA after allogeneic HCT.

Topics & Keywords

Cytomegalovirus and herpesvirus research Polyomavirus and related diseases Viral-associated cancers and disorders

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Clinical Infectious Diseases

Volume 57, Issue 5, pp. 671-681

DOI: 10.1093/cid/cit358

Field-Weighted Citation Impact: 7.38