Allelic Combinations of Immune-Response Genes Associated with Glatiramer Acetate Treatment Response in Russian Multiple Sclerosis Patients

201126 citationsJournal Article

Authors

Ekaterina Tsareva · Pirogov Russian National Research Medical University

О. Г. Кулакова · Pirogov Russian National Research Medical University

Alexey Boyко · Pirogov Russian National Research Medical University

С Г Щур

Dmitrijs Lvovs · Genetika

Alexander V. Favorov · Vavilov Institute of General Genetics

Е. И. Гусев · Pirogov Russian National Research Medical University

Abstract

The results suggest that the influence of immune-response genes on GA-induced response has a polygenic nature. The data are interpreted as evidence of additive and epistatic influences of the genes on GA efficiency for MS treatment.

Topics & Keywords

Multiple Sclerosis Research Studies Fibromyalgia and Chronic Fatigue Syndrome Research Rheumatoid Arthritis Research and Therapies

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Pharmacogenomics

Volume 13, Issue 1, pp. 43-53

DOI: 10.2217/pgs.11.136

Field-Weighted Citation Impact: 1.35