A Controlled Trial of Renal Denervation for Resistant Hypertension

20142,139 citationsJournal Article

Authors

Deepak L. Bhatt · Brigham and Women's Hospital

David E. Kandzari · Piedmont Atlanta Hospital

William W. O’Neill · Henry Ford Hospital

Ralph B. D’Agostino · Boston University

John M. Flack · Wayne State University

Barry T. Katzen · Baptist Hospital of Miami

Martin B. Leon ·

Abstract

This blinded trial did not show a significant reduction of systolic blood pressure in patients with resistant hypertension 6 months after renal-artery denervation as compared with a sham control. (Funded by Medtronic; SYMPLICITY HTN-3 ClinicalTrials.gov number, NCT01418261.).

Topics & Keywords

Blood Pressure and Hypertension Studies Heart Rate Variability and Autonomic Control Hemodynamic Monitoring and Therapy

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 370, Issue 15, pp. 1393-1401

DOI: 10.1056/nejmoa1402670

Field-Weighted Citation Impact: 212.34