The mgrB gene as a key target for acquired resistance to colistin in Klebsiella pneumoniae

2014307 citationsJournal Article

Authors

Laurent Poirel · University of Fribourg

Aurélie Jayol · Inserm

Séverine Bontron · University of Fribourg

María Virginia Villegas · Centro Internacional de Entrenamiento e Investigaciones Medicas

Melda Özdamar · Istanbul Medipol University

Salih Türkoğlu · Istanbul Medipol University

Patrice Nordmann

Abstract

The inactivation or down-regulation of the mgrB gene was shown to be a source of colistin resistance in K. pneumoniae. Interestingly, identical genetic events were identified among clonally unrelated isolates.

Topics & Keywords

Antibiotic Resistance in Bacteria Bacterial Genetics and Biotechnology Cancer therapeutics and mechanisms

Publication Details

Published in: Journal of Antimicrobial Chemotherapy

Volume 70, Issue 1, pp. 75-80

DOI: 10.1093/jac/dku323

Field-Weighted Citation Impact: 9.15

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The mgrB gene as a key target for acquired resistance to colistin in Klebsiella pneumoniae

Authors

Abstract

Topics & Keywords

Publication Details