Multiplexed DNA Detection with Biobarcoded Nanoparticle Probes

2006277 citationsJournal Article

Authors

Savka I. Stoeva · Northwestern University

C. Shad Thaxton · Northwestern University

Chad A. Mirkin · Northwestern University

Abstract

Sorting the mail: A highly selective assay for the detection of multiple DNA targets in solution was developed based on gold nanoparticles with oligonucleotide reporters. Four DNA targets associated with infectious viruses were detected simultaneously without enzymatic amplification at mid-femtomolar concentrations.

Topics & Keywords

Advanced biosensing and bioanalysis techniques Biosensors and Analytical Detection Advanced Biosensing Techniques and Applications

Publication Details

Published in: Angewandte Chemie International Edition

Volume 45, Issue 20, pp. 3303-3306

DOI: 10.1002/anie.200600124

Field-Weighted Citation Impact: 12.59

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Multiplexed DNA Detection with Biobarcoded Nanoparticle Probes

Authors

Abstract

Topics & Keywords

Publication Details