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Novel mutant-selective EGFR kinase inhibitors against EGFR T790M

2009989 citationsJournal Articlegreen Open Access

Authors

Wenjun Zhou · Dana-Farber Cancer Institute

Dalia Ercan · Center for Orthopaedics

Liang Chen · Dana-Farber Cancer Institute

Danan Li · Dana-Farber Cancer Institute

Marzia Capelletti · Center for Orthopaedics

Alexis B. Cortot · Dana-Farber Cancer Institute

Topics & Keywords

Lung Cancer Treatments and Mutations Quinazolinone synthesis and applications Cancer therapeutics and mechanisms

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Nature

Volume 462, Issue 7276, pp. 1070-1074

DOI: 10.1038/nature08622

Field-Weighted Citation Impact: 37.75

Novel mutant-selective EGFR kinase inhibitors against EGFR T790M | Researchclopedia

Lucian R. Chirieac

· Brigham and Women's Hospital

Roxana E. Iacob · Northeastern University

Robert F. Padera · Brigham and Women's Hospital

John R. Engen · Northeastern University

Kwok‐Kin Wong · Dana-Farber/Harvard Cancer Center

Nathanael S. Gray

Pasi A. Jänne · Dana-Farber Cancer Institute