Recurring Mutations Found by Sequencing an Acute Myeloid Leukemia Genome

20092,220 citationsJournal Articlebronze Open Access

Authors

Elaine R. Mardis · Washington University in St. Louis

Li Ding · New York Genome Center

David J. Dooling · New York Genome Center

David E. Larson · New York Genome Center

Michael D. McLellan · New York Genome Center

Ken Chen · New York Genome Center

Daniel C. Koboldt ·

Abstract

By comparing the sequences of tumor and skin genomes of a patient with AML-M1, we have identified recurring mutations that may be relevant for pathogenesis.

Topics & Keywords

Acute Myeloid Leukemia Research Multiple Myeloma Research and Treatments Protein Degradation and Inhibitors

UN Sustainable Development Goals

Life in Land

Publication Details

Published in: New England Journal of Medicine

Volume 361, Issue 11, pp. 1058-1066

DOI: 10.1056/nejmoa0903840

Field-Weighted Citation Impact: 107.00