Resolving spatial inconsistencies in chromosome conformation measurements

201320 citationsJournal Articlegold Open Access

Authors

Geet Duggal · Carnegie Mellon University

Rob Patro · Carnegie Mellon University

Emre Sefer · Carnegie Mellon University

Hao Wang · Carnegie Mellon University

Darya Filippova · Carnegie Mellon University

Samir Khuller · University of Maryland, College Park

Carl Kingsford ·

Abstract

Our filtering method for 3C data considers both metric consistency and statistical confidence simultaneously resulting in lower-error embeddings that are biologically more plausible.

Topics & Keywords

Genomics and Chromatin Dynamics Genomic variations and chromosomal abnormalities Gene expression and cancer classification

Publication Details

Published in: Algorithms for Molecular Biology

Volume 8, Issue 1, pp. 8-8

DOI: 10.1186/1748-7188-8-8

Field-Weighted Citation Impact: 0.60

Command Palette

Resolving spatial inconsistencies in chromosome conformation measurements

Authors

Abstract

Topics & Keywords

Publication Details