Autosomal Dominant Lateral Temporal Epilepsy: Clinical Spectrum, New Epitempin Mutations, and Genetic Heterogeneity in Seven European Families

2003138 citationsJournal Articlebronze Open Access

Authors

Roberto Michelucci · University of Bologna

Juan José Poza · Biogipuzkoa Health Research Institute

Vito Sofia · University of Catania

M. R. De Feo · Sapienza University of Rome

S. Binelli · Fondazione IRCCS Istituto Neurologico Carlo Besta

Francesca Bisulli · Istituto delle Scienze Neurologiche di Bologna

E. Scudellaro

Abstract

Our data confirm the inclusion of aphasic seizures within the ADLTE clinical spectrum, suggest the existence of locus heterogeneity in ADLTE, and provide new familial cases with LGI1 missense mutations associated with the disease.

Topics & Keywords

Cellular transport and secretion Autoimmune Neurological Disorders and Treatments Genetics and Neurodevelopmental Disorders

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Epilepsia

Volume 44, Issue 10, pp. 1289-1297

DOI: 10.1046/j.1528-1157.2003.20003.x

Field-Weighted Citation Impact: 2.76