Atorvastatin Prevents Gentamicin-Induced Renal Damage in Rats through the Inhibition of p38-MAPK and NF-kB Pathways

2009118 citationsJournal Articlegreen Open Access

Authors

Emin Özbek

Mustafa Çekmen · Kocaeli Üniversitesi

Yusuf Özlem İlbey

Abdülmuttalip Şimşek

Emre Can Polat

Adnan Somay · Bezmialem Foundation University Medical Faculty Hospital

Abstract

ATO acts in the kidney as a potent scavenger of free radicals to prevent the toxic effects of GM via the inhibition of MAPK and NF-kappaB signaling pathways and iNOS expression.

Topics & Keywords

Antimicrobial Resistance in Staphylococcus Antibiotics Pharmacokinetics and Efficacy NF-κB Signaling Pathways

Publication Details

Published in: Renal Failure

Volume 31, Issue 5, pp. 382-392

DOI: 10.1080/08860220902835863

Field-Weighted Citation Impact: 2.54

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Atorvastatin Prevents Gentamicin-Induced Renal Damage in Rats through the Inhibition of p38-MAPK and NF-kB Pathways

Authors

Abstract

Topics & Keywords

Publication Details