Palladium-Catalyzed Arylation and Heteroarylation of Indolizines

2004299 citationsJournal Article

Authors

Choul‐Hong Park · University of Illinois Chicago

Victoria Ryabova · University of Illinois Chicago

И. В. Серегин · University of Illinois Chicago

Anna W. Sromek · University of Illinois Chicago

Vladimir Gevorgyan · University of Illinois Chicago

Abstract

A highly effective protocol for palladium-catalyzed selective arylation and heteroarylation of indolizines at C-3 has been developed. Mechanistic studies unambiguously support an electrophilic substitution pathway for this transformation.

Topics & Keywords

Synthesis and Reactivity of Heterocycles Cyclopropane Reaction Mechanisms Synthesis and pharmacology of benzodiazepine derivatives

Publication Details

Published in: Organic Letters

Volume 6, Issue 7, pp. 1159-1162

DOI: 10.1021/ol049866q

Field-Weighted Citation Impact: 11.86

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Palladium-Catalyzed Arylation and Heteroarylation of Indolizines

Authors

Abstract

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Publication Details