Risk of Non-Hodgkin Lymphoma and Lymphoproliferative Precursor Diseases in US Veterans With Hepatitis C Virus

2007331 citationsJournal Article

Authors

Thomas P. Giordano · Baylor College of Medicine

Louise M. Henderson · Baylor College of Medicine

Ola Landgren · National Institutes of Health

Elizabeth Y. Chiao · Baylor College of Medicine

Jennifer R. Kramer · Baylor College of Medicine

Hashem B. El‐Serag · Baylor College of Medicine

Eric A. Engels

Abstract

Hepatitis C virus infection confers a 20% to 30% increased risk of non-Hodgkin lymphoma overall, and a 3-fold higher risk of Waldenström macroglobulinemia, a low-grade lymphoma. Risks were also increased for cryoglobulinemia. These results support an etiological role for HCV in causing lymphoproliferation and causing non-Hodgkin lymphoma.

Topics & Keywords

Hepatitis C virus research Viral-associated cancers and disorders Liver Disease Diagnosis and Treatment

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: JAMA

Volume 297, Issue 18, pp. 2010-2010

DOI: 10.1001/jama.297.18.2010

Field-Weighted Citation Impact: 12.58