Essential role for Argonaute2 protein in mouse oogenesis

2009117 citationsJournal Articlegold Open Access

Authors

Dónal O’Carroll · European Molecular Biology Laboratory

M. Azim Surani · University of Cambridge

Abstract

Our study shows that Ago2 has a key function in the mouse oocyte through global regulation of microRNA stability, and through this mechanism it affects gene expression in developing oocytes.

Topics & Keywords

Reproductive Biology and Fertility MicroRNA in disease regulation RNA Research and Splicing

Publication Details

Published in: Epigenetics & Chromatin

Volume 2, Issue 1, pp. 9-9

DOI: 10.1186/1756-8935-2-9

Field-Weighted Citation Impact: 11.45

Command Palette

Essential role for Argonaute2 protein in mouse oogenesis

Authors

Abstract

Topics & Keywords

Publication Details