Less-Tight versus Tight Control of Hypertension in Pregnancy

2015644 citationsJournal Articlebronze Open Access

Authors

Laura A. Magee · Centre for Advancing Health Outcomes

Peter von Dadelszen · B.C. Women's Hospital & Health Centre

Évelyne Rey · British Columbia Centre of Excellence for Women's Health

Susan Ross · B.C. Women's Hospital & Health Centre

Elizabeth Asztalos · University of Toronto

Kellie E. Murphy · Sunnybrook Hospital

Jennifer Menzies

Abstract

We found no significant between-group differences in the risk of pregnancy loss, high-level neonatal care, or overall maternal complications, although less-tight control was associated with a significantly higher frequency of severe maternal hypertension. (Funded by the Canadian Institutes of Health Research; CHIPS Current Controlled Trials number, ISRCTN71416914; ClinicalTrials.gov number, NCT01192412.).

Topics & Keywords

Pregnancy and preeclampsia studies Birth, Development, and Health Maternal and fetal healthcare

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 372, Issue 5, pp. 407-417

DOI: 10.1056/nejmoa1404595

Field-Weighted Citation Impact: 60.52