Hexanuclear self-assembled arene-ruthenium nano-prismatic cages: potential anticancer agents

2011137 citationsJournal Article

Authors

Vaishali Vajpayee · University of Ulsan

Yoon Jung Yang · Semyung University

Se Chan Kang · Semyung University

Hyunuk Kim · Pohang University of Science and Technology

In Su Kim · University of Ulsan

Ming Wang · University of Utah

Peter J. Stang ·

Abstract

Two novel nano-cage compounds, 8 and 9, were prepared by self-assembly of the ruthenium complexes 4 and 5, and the tripodal donor 1. The cytotoxicity of 8 was found to be considerably stronger than that of cisplatin. The complex 8 inhibited tumor cell proliferation by interfering into regulatory pathways of the cell cycle via apoptosis.

Topics & Keywords

Metal complexes synthesis and properties Supramolecular Chemistry and Complexes Ferrocene Chemistry and Applications

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Chemical Communications

Volume 47, Issue 18, pp. 5184-5184

DOI: 10.1039/c1cc10167f

Field-Weighted Citation Impact: 6.79