Developing a Clinically Feasible Personalized Medicine Approach to Pediatric Septic Shock

2014323 citationsJournal Articlegreen Open Access

Authors

Hector R. Wong · Cincinnati Children's Hospital Medical Center

Natalie Z. Cvijanovich · University of California, San Francisco

Nick Anas · Children's Hospital of Orange County

Geoffrey L. Allen · Children's Mercy Hospital

Neal J. Thomas · Penn State Milton S. Hershey Medical Center

Michael T. Bigham · Akron Children's Hospital

Scott L. Weiss

Abstract

We developed and tested a gene expression-based classification method for pediatric septic shock that meets the time constraints of the critical care environment, and can potentially inform therapeutic decisions.

Topics & Keywords

Adrenal Hormones and Disorders Sepsis Diagnosis and Treatment Renal function and acid-base balance

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: American Journal of Respiratory and Critical Care Medicine

Volume 191, Issue 3, pp. 309-315

DOI: 10.1164/rccm.201410-1864oc

Field-Weighted Citation Impact: 17.40