Associations Between Sex Steroids and the Development of Metabolic Syndrome: A Longitudinal Study in European Men

2015115 citationsJournal Articlebronze Open Access

Authors

Leen Antonio · KU Leuven

Frederick C. W. Wu · University of Manchester

Terence W O’Neill · University of Manchester

Stephen R. Pye · University of Manchester

Emma L. Carter · University of Manchester

Joseph D. Finn · University of Manchester

Martin K. Rutter ·

Abstract

In men, lower T levels, but not E2, are linked with an increased risk of developing MetS, independent of SHBG, BMI or insulin resistance. A lower E2/T ratio may be protective against developing MetS.

Topics & Keywords

Hormonal and reproductive studies Hypothalamic control of reproductive hormones Pharmacology and Obesity Treatment

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: The Journal of Clinical Endocrinology & Metabolism

Volume 100, Issue 4, pp. 1396-1404

DOI: 10.1210/jc.2014-4184

Field-Weighted Citation Impact: 11.62