Donepezil for the Treatment of Agitation in Alzheimer's Disease

2007324 citationsJournal Articlebronze Open Access

Authors

Robert Howard · King's College London

Edmund Juszczak

Clive Ballard · King's College London

Peter Bentham · Queen Elizabeth Hospital Birmingham

Richard G. Brown · King's College London

Roger Bullock

Alistair Burns · University of Manchester

Clive Holmes

Abstract

In this 12-week trial, donepezil was not more effective than placebo in treating agitation in patients with Alzheimer's disease. (ClinicalTrials.gov number, NCT00142324 [ClinicalTrials.gov].).

Topics & Keywords

Dementia and Cognitive Impairment Research Healthcare Decision-Making and Restraints Psychiatric care and mental health services

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 357, Issue 14, pp. 1382-1392

DOI: 10.1056/nejmoa066583

Field-Weighted Citation Impact: 14.41